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Re: DewDiligence post# 8

Tuesday, 03/09/2021 9:39:35 AM

Tuesday, March 09, 2021 9:39:35 AM

Post# of 24
MTCR starts phase-2a for MET642—the follow-on FXR agonist to MET409:

https://finance.yahoo.com/news/metacrine-initiates-phase-2a-trial-113000073.html

The Phase 2a clinical trial is a 16-week, randomized, placebo-controlled, multi-center trial evaluating the safety, tolerability and pharmacological activity (as measured by liver fat reduction) of MET642 (3 mg and 6 mg) vs placebo. An interim analysis is planned in the fourth quarter of 2021, after approximately 60 patients have completed 16 weeks of treatment. Topline trial results of up to 180 patients are expected to be reported in the first half of 2022.

See #msg-162210410 for related info.

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