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Friday, February 26, 2021 10:45:55 AM
First thing I recall on CD12 that stuck me was someone claiming to have advance mathematics degrees going into great detail while their statistical models unequivocally “proved” CD12 was a failure... The multiple MS in mathematics is impressive if true, but hard to verify the validity of such a claim when the person’s identity is unknown... Nevertheless, I reviewed most of this individuals posts related to statistics and actually found them very convincing as a novice of statistical analysis. However, I’ve been told using “absolute” terms in statistics are normally frowned upon...
The math is quite easy. They need > 31% mortality rate for severe-to-critical SoC arm in order to achieve a p-value < 0.05. That math is simple. The comparable study is more of an art but it seems very obvious that most recent critical SoC arms have a mortality rate of 30-35% and severe has 10-15%. So it seems impossible to have a severe-to-critical SoC mortality > 31%. It is very easy math.
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