I prefer PFE for a few reasons. First, I expect PFE’s Prevar-20 to dominate MRK’s V114 in what is shaping up to be a very large global market for next-generation pneumococcal vaccines. The COVID-19 epidemic has underscored the importance of pneumococcal vaccination insofar as many deaths attributed to COVID-19 are actually cases of secondary bacterial pneumonia.
With wider coverage against the various pneumococcal strains, Prevnar-20 is simply a better product than V114, and I view this market as one where the better product ends up taking an overwhelming market share.