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Rock, Misui New Vitamin D Info

Extracts in inverted commas taken from following:
From https://medicalxpress.com/news/2020-11-reveals-gut-bacteria-vitamin-d.html

Ref. Vitamin D metabolites and the gut microbiome in older men
https://www.nature.com/articles/s41467-020-19793-8

Study published in recent weeks reveals connection between gut bacteria and vitamin D levels
by Heather Buschman, PhD, University of California - San Diego

SOME GREAT FINDINGS HERE

“The team analysed stool and blood samples contributed by 567 men participating in six cities around the United States, their mean age was 84.

Our gut microbiomes—the many bacteria, viruses and other microbes living in our digestive tracts—play important roles in our health and risk for disease in ways that are only beginning to be recognized.

Vitamin D can take several different forms, but standard blood tests detect only one, an inactive precursor that can be stored by the body. To use vitamin D, the body must metabolize the precursor into an active form.
The variety of bacteria types in a person's gut—was closely associated with active vitamin D, but not the precursor form.
In addition to discovering a link between active vitamin D and overall microbiome diversity, the researchers also noted that 12 particular types of bacteria appeared more often in the gut microbiomes of men with lots of active vitamin D. Most of those 12 bacteria produce butyrate, a beneficial fatty acid that helps maintain gut lining health.
The team unexpectedly found no correlations between where men lived (and thus exposure to sunlight) and their levels of active vitamin D hormone.”
"It seems like it doesn't matter how much vitamin D you get through sunlight or supplementation, nor how much your body can store," Kado said. "It matters how well your body is able to metabolize that into active vitamin D, and maybe that's what clinical trials need to measure in order to get a more accurate picture of the vitamin's role in health."

Rock, Misiu, when you advocate extremely large doses of Vitamin D, do we know how much becomes active vitamin D?