Mymetics Corp (MYMX)

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Interesting:
cGAS-STING-TBK1-IRF3/7 induced interferon-ß contributes to the clearing of non tuberculous mycobacterial infection in mice.
Ruangkiattikul N1, Nerlich A1, Abdissa K1, Lienenklaus S2, Suwandi A2, Janze N1, Laarmann K1, Spanier J3, Kalinke U3, Weiss S2, Goethe R1
Author information
Affiliations
6 authors
1. Institute for Microbiology , University of Veterinary Medicine Hannover , Hannover , Germany.
3 authors
2. Department of Molecular Immunology , Helmholtz Centre for Infection Research , Braunschweig , Germany.
2 authors
3. Institute for Experimental Infection Research, TWINCORE Centre for Experimental and Clinical Infection Research , a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School , Hannover , Germany.

Type I interferons (IFN-I) such as IFN-a and IFN-ß are pleiotropic cytokines involved in various infections and inflammatory reactions as well as in cancer surveillance.1 The protective role of IFN-I against many viral infections is well established.2 IFN-I are also induced during bacterial infection. Here they have been shown to be either protective or detrimental, depending on the type of bacteria and the route of infection.3
http://europepmc.org/article/MED/28422568