I personally think (actually, know) that ambient superconductors are around the corner within 10 years and indeed will be a disruptive technology, I cannot discuss this subject in public due to conflict of interests (I have 16 patents of my own in the field and just last week another went to the PTO). Al I can say, it will have disruptive effects on both Power (generation, transmission and use), and IT in general (just think of the effort that went into moving from Al to Cu in I-lines, for a "puny" 40% improvement in conductivity).
In the medical field, I think that the disruptions will occur from a few not connected technologies. For instance, taking patients out of the hospital back into their homes. That could be facilitated by a number of technologies, some of which might involve "automation of healing" using each patient own physiological resources. Unless the immune system is "completely shut down" or suddenly "overwhelmed", it is the best source of therapeutic agents for most afflictions. But the immune system is quite "personal", thus the difficulty of mimicking it with any type of drugs. The breakthrough, I think, will involve replication (via cell and DNA replication) of the few immune agents already present (for a given pathology) and overdosing back the patients with such agents. That will require a "microcosmos" of a pharmaceutical (I should say, a microfermentor) plant at the patient bed side, some rapid and accurate analytical tools, and few other things, and that is probably mor like 20 years out. A second major process is of course connected with the geriatrification of the population. Not just the health care demands of such a population, but many other activities (they will be much healthier than the geriatrics of the last generation) which will provide a new type of market (food, transportation, entertainment and home based micro businesses).
I really do not have sufficient time to go into further speculations on that field....