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Re: VuBru post# 289857

Tuesday, 06/16/2020 5:41:42 PM

Tuesday, June 16, 2020 5:41:42 PM

Post# of 822439
I believe they had defined a fairly clear analytic plan even in the protocol, and I do believe there was a statistician working with the DMC out of the North Carolina Wake Forest area - who I'm thinking was likely brought in via Curt Furberg, the original DMC chair, who also served at the same time on the SAB for the competing dendritic cell company Immunicum, and whose brother served on the same, as well as the BOD for that same company (unbeknownst to NWBO).

But it was never really clear in the protocol as to how they intended to measure PFS and OS, only that there was .02 dedicated to PFS. That's why I've always thought there was .02 for PFS, and if it was stat sig, that .02 moved over to OS giving it .05 instead of just .03. But again, this was never made clear.

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