Agree animal models don't always work and historical failure rate is high.
The important part of my post that you didn't quote or seem to consider is the destruction of virus outside a cell and not interacting with host cells much. Those types of drugs would have much higher probability of success in humans following success in animals, theoretically - since all such drugs are doing is reducing viral load and keeping virus from spreading to infect other cells or other people.
Limiting spread of viral infection is good. Hope some day to see if the concept works or not in humans.
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