Amarin Corp Plc (AMRN)

[circuitcity]

Quite:
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Applicant was able to overcome the above 103 obviousness rejection by showing: … The prior art is either silent or teaches that there is no statistically significant change in Apo-B levels when patients with TG levels less than 150 mg/dl or between 150-499 mg/dl are treated with either 96% pure ethyl-EPA or a mixture of ethyl-EPA and DHA

Kurabayashi teaches differently:_ ss changes in Apo-B exist.
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Hdg,

Can we say we have established per mc1988 that Kura did not reach us there is ss apoB reduction with epa, instead of e + epa (not epa + e either,seems to me more focus on e for this study)

Kura trial base line trig: 150 - 400, study group: 1800mg epa + 2mg e, purity 99.8%
Control group: 2mg e only?

I am wondering where re those number coming from in PTO quote: 150, 499 and 96%. He gave no reference, maybe you can find them. Thanks a lot for doing this by the way.