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Sunday, April 05, 2020 12:08:37 PM
No, I am not. I know / saw both of them. The ss change in the EPA + e arm is enough for hypothesis.
Not sure I agree with that HDG, you cannot take a piece of data in isolation for hypothesis generation:
- If you have a statistical significant difference between arm, you can hypothesize that EPA alone may reduce ApoB
-If you have a change (either direction) in the arm that you combine with another lipid modifying agent (estriol) you cannot reasonable make the hypothesis that EPA reduces ApoB without comparing to your control arm. Maybe in the legal-world or patent-world that is OK but there is no way in my mind that a POSA would find that conclusion reasonable neither would find that sufficient for hypothesis generation
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