MEDICAL NEWS | PHYSICIAN'S FIRST WATCHCARDIOLOGY March 18, 2019
New Guidelines Back off Aspirin for Primary Cardiovascular Prevention
By Kelly Young
Edited by Susan Sadoughi, MD, and André Sofair, MD, MPH
New guidelines say that daily, low-dose aspirin should be used infrequently to prevent primary cardiovascular disease. The American College of Cardiology and the American Heart Association conclude that aspirin should be reserved for people with the highest cardiovascular risk and the lowest risk for bleeding.
The guideline categorically recommends against aspirin use in those over age 70 and in those at high risk for bleeding, such as patients with chronic renal disease or thrombocytopenia. The guidelines were published in JACC and Circulation and presented at ACC's annual meeting.
Among the groups' other recommendations:
For patients with type 2 diabetes and other cardiovascular risk factors, metformin is the first-line treatment. GLP-1R agonists and SGLT-2 inhibitors may now be considered to help reduce CVD risk.
Adults should aim to get at least 150 minutes of moderate or 75 minutes of vigorous physical activity a week, which is consistent with prior guidance.
Statins are recommended with lifestyle changes for patients with elevated LDL levels (at or above 190 mg/dL), type 2 diabetes, or other cardiovascular risk factors.