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Re: Cmed123 post# 225805

Monday, 08/05/2019 11:52:00 AM

Monday, August 05, 2019 11:52:00 AM

Post# of 257401

ENTA...any reason for the weakness?

Some investors may be skittish about the phase-2a data for EDP-305 in NASH that are due any day (#msg-145935658), and may be reported in conjunction with ENTA’s quarterly financials tomorrow after the close.

The concern with EDP-305 (an FXR agonist) is a potential safety problem (#msg-146937904). ENTA’s phase-2a trial won’t give much of a read on efficacy because there are no biopsies and the primary endpoint is change in ALT. The main point of the phase-2a trial is to select the dose(s) to advance in phase-2b.

…do you think [ENTA is]…attractively valued?

Yes, I do. ENTA’s pipeline and Mavyret-royalty stream gives it considerable buyout vig, IMO.

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