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Re: hopeforthefuture2 post# 234758

Thursday, 06/27/2019 1:55:00 PM

Thursday, June 27, 2019 1:55:00 PM

Post# of 823022
hopeforthefuture, about David Innes' description of beta lock you are right. I misinterpreted DI's description of the soft data lock. Looking back he said that there is an interval during which no results will be added. I misinterpreted that he meant hard lock but that can't be because after hard lock we need no time interval. Unblinding can proceed immediately.

I think now I understand what is happening. It is now almost June and the soft data lock has not yet been installed. Any event can still be accepted in the data base and we are almost in July and almost 47 months past the last surgery. That is a long time and maybe we will have a few more months before the new events will not be entered. I am betting that the attrition rate is so low now, that the pending soft data lock will not be very important and will not exclude crucial data.

The trouble is that for me to decipher the content of DI's message is like unlocking the Rosetta Stone. I know that DI is not allowed to give us material information so he has to keep his answers vague and ambiguous. That is not his fault.
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