According to the research report, “Dehydroepiandrosterone (DHEA) and its sulfated form (DHEAS)—jointly referred as DHEA(S)—are neurosteroids that serve important functions that help to regulate brain development, function, and behavior. DHEA(S) are purported to exert a cognitive-preserving effect through their neuroprotective, antioxidant, anti-inflammatory, and antiglucocorticoid actions.”
The team wrote that prechemotherapy DHEA(S) levels “were found to be associated with impairment in the self-perceived cognitive domains of verbal fluency,” and “mental acuity.”
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