Anavex Life Sciences Corp (AVXL)

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Alzheimer’s and Parkinson’s Disease: Similarities and Differences
James M. Ellison, MD, MPH
Swank Memory Care Center, Christiana Care Health System

https://www.brightfocus.org/alzheimers/article/alzheimers-and-parkinsons-disease-similarities-and-differences

Cognitive Decline

Cognitive decline is common in both AD and PD, though significantly less common in PD. As many as half of people with PD develop cognitive difficulties, which can range from mild forgetfulness to full-blown dementia. The dementia of PD is called “subcortical” because of the location of affected brain areas, and subcortical dementias have somewhat different clinical symptoms than a “cortical” dementia like AD. In PD dementia, slowed physical activity can be accompanied by slowed thinking and by problems with memory that are more responsive to reminders than those of AD because the difficulty is with memory retrieval rather than, as in AD, with storage of new learning.

Further Reading:

Aarsland D, Larsen JP, Lim NG, et al. Range of neuropsychiatric disturbances in patients with Parkinson’s disease. J Neurol Neurosurg Psychiatry 1999;67:492-6.

Aarsland D, Cummings JL, Larsen JP. Neuropsychiatric differences between Parkinson’s disease with dementia and Alzheimer’s disease. Int J Geriatric Psychiatry 2001;16:184-91.

Weintraub D, Stern MB. Psychiatric complications in Parkinson Disease. Am J Geriatr Psychiatry
2005;13(10):844-51.

Some of Anavex Scientific Advisors have YEARS of knowledge on these topics. I'm pretty confident that the TGD and his team have done their DD to have the best shot to "score" with these MULTIPLE shots on goal. imho

Patience and Perspective