Anavex Life Sciences Corp (AVXL)

[XenaLives]

Catechol the chemical - fact sheet:

Uses
Catechol is used as a photographic developer, a developer for fur dyes, as an intermediate for antioxidants
in rubber and lubricating oils, in polymerization inhibitors, and in pharmaceuticals. (1,3,4)
Sources and Potential Exposure
Catechol may be released into the environment during its manufacture and use. (1)
The major routes of human exposure are consumption of contaminated drinking water and ingestion of
contaminated food. (1)
Catechol occurs naturally in fruits and vegetables. (7)
It has been detected in cigarette smoke. (7)
Assessing Personal Exposure
No information was located regarding the measurement of personal exposure to catechol.
Health Hazard Information
Acute Effects:
Skin contact causes eczematous dermatitis in humans. (1,3-6)
In humans, absorption through the skin results in an illness resembling that induced by phenol, except
convulsions are more pronounced. (1,5,6)
Large doses of catechol can cause depression of the CNS and a prolonged rise of blood pressure in
animals. The rise of blood pressure appears to be due to peripheral vasoconstriction. (1,5,6)
Due to the lack of information regarding the duration of exposure in the above studies, it is not clear
whether these health effects were observed following acute or chronic exposure.
Acute animal tests in rats, mice, guinea pigs, and rabbits have demonstrated catechol to have high acute
toxicity by oral or dermal exposure. (2)

Chronic Effects (Noncancer):
No information is available on the chronic effects of catechol in humans or animals.
EPA has not established a Reference Concentration (RfC) or a Reference Dose (RfD) for catechol.
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ttps://www.epa.gov/sites/production/files/2016-09/documents/catechol-pyrocatechol.pdf

Pharma has stepped off the deep end or scientific knowledge and doesn't have a leg to stand on.

An informed patient can no longer trust the safety of any medicine approved and prescribed under 20th century protocols.

Precision medicine must be implemented ASAP and environmental protection and remediation is just as important. We are killing the planet and we are killing millions around the world if we continue to ignore science.