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Re: iclight post# 212725

Monday, 02/04/2019 5:23:03 PM

Monday, February 04, 2019 5:23:03 PM

Post# of 824048
" and expression of four ICT-107 targeted antigens in pre-immunotherapy tumors correlated with prolonged OS and PFS in GBM patients"

This kind of plays well into the WTL and the beauty of targeted personalized medicine. The more (Targets) expressed, that matched ICT's "pre-selected" targets , the greater the outcome. That is the problem in treating a heterogeneous population with the same drug and expecting it to work for everyone. We have to get better at treating an individuals disease.


Just think if Eye Doctors where like Oncologists, When you go to the eye doctor, they don't just say yep you can't see perfectly(have breast cancer) and here take these same prescriptions lenses(monoclonal antibody or checkpoint) we gave the last person, we saved money by buying a boatload of the same prescription glasses in bulk. They seem to work really well for about 15% of the population.


DCVAX matches treatment to patient. It's not perfect but it is an important first step.
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