Anavex Life Sciences Corp (AVXL)

[Investor2014]

I believe it throws some new light on things, although the subject matter is also not within my core competencies.

The fact that the endogenous, the body's own, Sigma-1 Receptor agonists have not been fully understood and therefore what and how the firetruck is called from the station when there is a fire, makes it more difficult to understand the actual MOA of A2-73.

I think the paper, among other things, may offer some clues to why Donepezil, having higher binding to S1R, seems to work less well than A2-73.