Anavex Life Sciences Corp (AVXL)

[XenaLives]

About MS:

From this morning's reading I think that the MS science landscape is not ready for an Anavex 2-73 trail yet and this is the only reason we haven't heard anything on MS. This could also explain why it was pulled from the pipeline page.

From myelinrepair.org:

RECENT UPDATES


March 2018
MRF funds experiment at the Karolinska Institute in Sweden to look for biomarkers of repair in CSF of MS patients.

February 2018
MRF begins collaborating with Biogen to try to image specific metabolic compounds to determine if they indicate demyelination or remyelination.

February 2018
MRF sends research agreement to Stanford to examine if novel retinal imaging techniques can measure recovery / repair in MS patients.

December 2017
William K. Bowes, Jr. Foundation awards $750,000 to MRF for biomarker research.

This indicates that biomarkers are an issue, and possibly the delay for studies concering 2-73 and MS.

November 2017
Oregon Health & Science University begins study to investigate if T1 relaxometry can be used to determine the quality of repaired myelin

October 2017
Wilson Sonsini Goodrich & Rosati, Silicon Valley’s preeminent law firm, very generously continues to handle all MRF’s legal work on a pro bono basis.

September 2017
MRF begins funding biomarker related experiments in Europe and the United States.

Summer 2017
MRF prioritizes initial key biomarker questions and experiments.

May 2017
MRF creates biomarker Executive Committee consisting of clinicians, academics and pharmaceutical industry veterans.

April 2017
Penates Foundation continues their support for MRF with a new gift.

https://www.nationalmssociety.org/About-the-Society/News/CMSC-Meeting-Features-Solutions-to-Help-People-wit

http://www.myelinrepair.org/research_achievements.shtml


Wikipedia on the Myelin Repair Foundation - interesting history, some of the info is dated but check out the chart titled "vte
Multiple sclerosis and other demyelinating diseases of CNS (G35–G37, 340–341)", some good info on demyelinating disease and current treatments:

https://en.wikipedia.org/wiki/Myelin_Repair_Foundation


From NationalMSSociety.org:

CMSC Meeting Features Solutions to Help People with MS Live Their Best Lives
June 15, 2018

More than 2,300 MS healthcare providers, researchers, people living with MS, and others gathered at the 32nd Annual Meeting of the Consortium of MS Centers (CMSC) in Nashville in May 2018 to share findings and learn the latest about diagnosing and treating MS, and to hear MS research updates. The meeting also focused on solutions that help people with MS to live their best lives. Selected presentations from the meeting are posted here, and a pdf of the abstracts is also available. Below are a few highlights of the meeting, and a blog is posted here. Where available, links are provided to the presentations/abstracts.

“iScreening” for Cognitive Problems: Dr. Stephen Rao (Cleveland Clinic) discussed the MS Performance Test (MSPT), an iPad®-based tool for assessing cognitive function, during the John F. Kurtzke Memorial Lecture. “Many cognitive relapses probably occur but are not picked up, so we miss the opportunity to intervene,” he said, explaining that people with MS do not always perceive their own cognitive problems, so don’t report them. The MSPT is designed to quantify major cognitive symptoms and other outcomes associated with MS. People arrive early for their regular appointments and administer the test themselves, and results are transferred to the doctor immediately. A version is available for free to healthcare providers at www.biogenapp.com. View this presentation

https://www.nationalmssociety.org/About-the-Society/News/CMSC-Meeting-Features-Solutions-to-Help-People-wit