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Investor2014

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Re: OFP post# 176703

Sunday, 12/30/2018 4:31:34 AM

Sunday, December 30, 2018 4:31:34 AM

Post# of 517620

The ratio of donepezil to total radioactivity in brain was 86.9 to 93.0%, indicating low permeability of the metabolites through the blood-brain barrier.


Absorption, distribution, metabolism, and excretion of donepezil (Aricept) after a single oral administration to Rat.
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