Friday, December 28, 2018 10:46:20 AM
I’ve Done My Own Private Spreadsheet On This
On a spreadsheet, I’ve punched in all of the controlling numbers I could find to answer this big question (and others). I will keep the spreadsheet to myself — would merely prompt naysayers to claim I’d be pumping Anavex.
But anyone who can use a spreadsheet can run the potential ranges themselves. Here are the controlling factors (as I see them):
1. The names and numbers of the diseases and conditions to be treated.
(Right now, Rett syndrome, Parkinson’s, and Alzheimer’s. Very likely to be more, including insomnia.)
2. Number of cases of each condition annually in the US.
(Potential number of patients.)
3. Number of cases of each condition annually in the rest of the world.
(Potential number of patients globally.)
4. Anticipated annual per-patient revenues for each condition, in each geographic region.
5. Total annual corporate revenues.
6. Estimated after-costs corporate revenues.
7. Estimated drop-down funds going out as per-share dividends.
8. Estimated price/earnings ratio, to estimate share price and market capitalization.
All of these metrics must be stated as ranges, not solid integers.
For some who post often here, no need for a spreadsheet. Zero times any number is zero. For them, they are certain Anavex clinical trials will yield no validating, positive clinical outcomes. No need for the trials themselves. Anavex 2-73 is a central nervous system treatment zero from the start. End of game, before it starts.
But for others, punch the numbers. See the potential ranges of all of the metrics.
[Is it possible]...these drugs will achieve mega-blockbuster drug status with sales of at least several billion dollars per year?
But anyone who can use a spreadsheet can run the potential ranges themselves. Here are the controlling factors (as I see them):
1. The names and numbers of the diseases and conditions to be treated.
(Right now, Rett syndrome, Parkinson’s, and Alzheimer’s. Very likely to be more, including insomnia.)
2. Number of cases of each condition annually in the US.
(Potential number of patients.)
3. Number of cases of each condition annually in the rest of the world.
(Potential number of patients globally.)
4. Anticipated annual per-patient revenues for each condition, in each geographic region.
5. Total annual corporate revenues.
6. Estimated after-costs corporate revenues.
7. Estimated drop-down funds going out as per-share dividends.
8. Estimated price/earnings ratio, to estimate share price and market capitalization.
All of these metrics must be stated as ranges, not solid integers.
For some who post often here, no need for a spreadsheet. Zero times any number is zero. For them, they are certain Anavex clinical trials will yield no validating, positive clinical outcomes. No need for the trials themselves. Anavex 2-73 is a central nervous system treatment zero from the start. End of game, before it starts.
But for others, punch the numbers. See the potential ranges of all of the metrics.
Recent AVXL News
- Anavex Life Sciences Highlights New Scientific Findings on Shared Biology Between Autism and Alzheimer’s Disease • GlobeNewswire Inc. • 04/14/2026 11:30:00 AM
- Anavex Life Sciences to Present at the 25th Annual Needham Virtual Healthcare Conference • GlobeNewswire Inc. • 04/07/2026 11:30:00 AM
- Anavex withdraws EU approval filing for Alzheimer’s therapy • IH Market News • 03/30/2026 12:39:26 PM
- Anavex Life Sciences Provides Comprehensive Regulatory Update • GlobeNewswire Inc. • 03/30/2026 11:30:00 AM
- Form 8-K - Current report • Edgar (US Regulatory) • 03/25/2026 08:06:00 PM
- Anavex withdraws EU marketing application for Alzheimer’s therapy blarcamesine • IH Market News • 03/25/2026 02:06:58 PM
- Anavex Life Sciences Provides Update on Regulatory Review in the EU for Blarcamesine to Treat Early Alzheimer’s Disease • GlobeNewswire Inc. • 03/25/2026 11:30:00 AM
- Anavex Life Sciences Presents New Data from its AD-004 Phase IIb/III Trial at AD/PD 2026 Conference Demonstrating Consistent Correlation Between the Treatment Effect of Oral Blarcamesine and Preservation of Brain Volume in Early Alzheimer’s Disease • GlobeNewswire Inc. • 03/23/2026 11:30:00 AM
- New Scientific Findings Highlight Hypothesis of Autophagy Failure as a Precursor of Amyloid Beta and Tau Pathology in Alzheimer’s Disease • GlobeNewswire Inc. • 03/20/2026 11:30:00 AM
- Anavex Life Sciences Presents Significant Treatment Effects of Blarcamesine in New Advanced Alpha-Synuclein Model of Parkinson’s Disease at AD/PD 2026 Conference • GlobeNewswire Inc. • 03/17/2026 11:30:00 AM
- Anavex Life Sciences to Present at the Citizens Life Sciences Conference • GlobeNewswire Inc. • 03/03/2026 12:30:00 PM
- Anavex Life Sciences to Present at the 46th TD Cowen Annual Health Care Conference • GlobeNewswire Inc. • 02/25/2026 12:30:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/25/2026 11:07:01 AM
- Anavex Life Sciences Appoints Seasoned Healthcare Leader to Board of Directors • GlobeNewswire Inc. • 02/23/2026 12:30:00 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 02/09/2026 09:40:27 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/09/2026 12:31:17 PM
- Anavex Life Sciences Reports Fiscal 2026 First Quarter Financial Results and Provides Business Update • GlobeNewswire Inc. • 02/09/2026 12:30:00 PM
- Anavex Life Sciences to Announce Fiscal 2026 First Quarter Financial Results on Monday, February 9, 2026 • GlobeNewswire Inc. • 02/03/2026 12:30:00 PM
- Anavex Joins ACCESS-AD, a Major Initiative Funded by the European Commission, Through the Clinical Evaluation of Blarcamesine as Part of a Precision Medicine Approach in Alzheimer’s Disease • GlobeNewswire Inc. • 01/13/2026 12:30:00 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 01/09/2026 10:26:26 PM
- Edelson Lechtzin LLP Announces an Investigation of Anavex Life Sciences Corp. (NASDAQ: AVXL) and Encourages Investors with Substantial Losses Contact the Firm • PR Newswire (US) • 01/09/2026 01:13:00 AM
- Anavex Life Sciences Appoints Senior Vice President Global Head of Neurology • GlobeNewswire Inc. • 01/08/2026 12:30:00 PM
- Anavex Life Sciences Receives FDA Feedback on Alzheimer’s Disease Program • GlobeNewswire Inc. • 01/06/2026 12:30:00 PM
- Anavex Life Sciences Submitted Request for EMA to Re-Examine Its Opinion • GlobeNewswire Inc. • 12/18/2025 12:30:00 PM
- Anavex Life Sciences Provides Update on Regulatory Review in the EU for Blarcamesine to Treat Early Alzheimer’s Disease • GlobeNewswire Inc. • 12/12/2025 09:05:00 PM
