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OFP

Re: falconer66a post# 175836

Saturday, 12/22/2018 12:21:08 PM

Saturday, December 22, 2018 12:21:08 PM

Post# of 517311

The molecular architecture of Anavex 2-73, however, very closely (perhaps exactly) matches the binding sites of the sigma-1 receptor proteins in the neuron. It makes a strong molecular connection, a binding fit, to the cellular structures and chemistries that control, chaperone, (among other things) calcium signaling between the endoplasmic reticulum and the mitochondrion.

Is there evidence to support those assertions relative to other known agonists? Why would you make this statement? There is certainly evidence AGAINST a relatively "strong molecular connection".
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