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Re: OFP post# 170036

Saturday, 10/27/2018 4:41:37 PM

Saturday, October 27, 2018 4:41:37 PM

Post# of 517593
There is so much discussions on the numbers.

If someone who talks to IR asks company to clarify the simple information such as

If co can show some cooperation, this could be easier for all.


1. What is the definition of dosing?

Low. 10-20
Medium. 30-40
High. 50


2. How many patients were in each group for final analysis?

3. Did all high concentration patient came from high dosing?

Or high concentration patients came with
High dosing
Medium dosing + APOE carriers?

Did APOE carrier + 50 mg had the highest concentration

4. Will all patients in P2/3 trial get high dosing?

5. Will the APOE carrier check will be done before dosing and then dosing will be decided?
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