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Re: Investor2014 post# 169976

Saturday, 10/27/2018 8:16:15 AM

Saturday, October 27, 2018 8:16:15 AM

Post# of 517499
investor2014: Congratulations for a very well done assessment:
Summary discussions? What's next?

A drop in MMSE score clearly measurable early in suspected AD is a good diagnostics method, whereas maintaining Activities of Daily Living is what counts as clinically meaningful as we all age.

Now Anavex just have to get those damn trials on the go to confirm, I think we a high degree of likelihood, that A2-73 does work and isn't t****!

I suspect, as others point out, that overall the market is not aware of or have turned the blind eye towards Anavex and their small n un-controlled open label trial. A2-73 is everything other than what the old school have learned about AD. I think over the weeks to follow this will gradually change not least on the backdrop of increasing scepticism and reviews of Biogen and other BP attempts in the Antibody space of Amyloid plaque and Tau tangle fighting.

Time and science is on our side!



Thanks for your time and assessment. think about the what's next action? As you suggest time is all we got here and sooner is generally better. Will WW regulatory bodies and or BP study these results or will they be dismissed until the (ever/always) next trial (bigger/better) syndrome get set? The science seems w/o doubt compelling.

I agree that BIIB has been openly talking down it's latest AD effort. In fact I would not be surprised if they quietly folded that tent.

I am anxiously expecting the FDA and or selected BP (Phyizer-Amgen)to react w/some kind of special process treatment for AVXL trials and for BP to express support/interest in co-trials-partnering for other indications along w/AD. Wishful thinking yes, but not out of the question. Your ongoing Thoughts?, and thanks again.
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