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Re: Steady_T post# 168974

Saturday, 10/20/2018 12:50:06 PM

Saturday, October 20, 2018 12:50:06 PM

Post# of 518983

A careful reading of the PR suggests that the 15 person trial is to do dose titration and determine what doses are appropriate for the large placebo controlled follow on trial.


Good analysis. Is the 15 patient study also described as double blind placebo controlled, or is that only describing the follow on study? Can you comment on that? A 15 patient placebo controlled study is important in that, if an efficacy signal is detected, though small N, it will have some legitimacy and withstand the scrutiny the 32 patient AD trial has suffered from. Your thoughts?

IMHO
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