IOVA is the old LBIO Tumor Infiltrating Lymphocytes ( TILs ) is the platform upon which its deep pipeline is based. TILs are isolated from a patient's tumor following resection and expanded in vitro away from the cancer's immune suppressing effects. IOVA has 10 Ph2 programs and 2 Ph1 programs. Its lead program received Orphan Drug designation for the treatment of Cervical Cancer The rise of neoantigens may render this platform relatively useless.