Tuesday, October 17, 2017 8:00:01 AM
Senti, is he purported to have:
1. Denied an IA was performed in summer 2015? Or
2. Denied the trial failed in the summer of 2015? Or
3. Denied a futility rec in the summer of 2015?
I don't believe he is purported to have denied 1 or 3 above. I believe some have interpreted a denial of 2 above to mean a denial of 3. They are not the same thing.
Regarding your AA scenario : have you read the recently published Rindo paper in Lancet? Did you see what they said about historical controls? It was presented as an old lesson relearned.
"Even carefully assembled historical controls can be misleading and an unsuitable basis for clinical trial designs"
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