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Re: marzan post# 132940

Monday, 09/04/2017 10:29:56 AM

Monday, September 04, 2017 10:29:56 AM

Post# of 821030
marzan, the majority of the 100 alive in June were PFS. Around 12/16 or 1/17 there were around 83 PFS. Based on the death rate of 2 per month since June I am assuming an equal rate of about 2 progressions per months from 12/16 or 1/17. In June we would have therefore ended up with about 71-73 PFS among the 100 survivors. Even if a few patients were lost (LTFU) the PFS constitute a clear majority among the 100 alive.

This would not prove that PFS was a success since we don't know whether the difference between controls and trial was SS but it does show that a very large proportion of the patients (maybe a subtype(s)?) had delayed progression and an extended survival and it would strongly suggest that DCVax-L was responsible.
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