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Re: DewDiligence post# 212608

Monday, 07/24/2017 8:25:21 PM

Monday, July 24, 2017 8:25:21 PM

Post# of 252290
AF:

I'm just guessing here, but it would be the type of deviousness worthy of AF.

Since SRPT was controversially approved based on a surrogate outcome, there is a chance that the post-market trials the company is obligated to run end up failing. In the case of this MRK news, AF may be making a list of people / goading people into arguing that the pembro approval based on the surrogate should not be revoked based on this survival outcome.

If / when the time comes that SRPT's follow-on trials show little effect, AF may start calling people out for advocating eteplirsen withdrawal when they looked the other way for pembro in SCCHN.

I think it's very much apples and oranges, given the preponderance of data validating the activity of pembro as a drug. But it's a typical twitter-type long term argument.

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