Also, having a strong affinity to S1R as no direct relation to efficacy. Case in point, an antagonist can have a very strong affinity to S1R and obviously would work in a negative fashion.
So, not only is being an S1R agonist paramount, but must be in an efficacious manner. As mentioned earlier, 2-73's metabolite is likely a key aspect of 2-73's overall efficacy.
Market Data 
Markets 
AI
