Thank you for the clarification. Your explanation of the placement of that first red dot is what I understood you to mean except that I was also trying to get clarification about why you believe PFS would be low to begin with. This is why I interjected what I believed to be your past point about early apparent eventing being called progression due to potential faulty adjudication of pseudo progression. While pseudos should be balanced out, the potential for PFS benefit is lost and this might then drop that red dot into the zone you placed it in. I hope this makes sense. I would like your explanation of why you think the red dot might be where you placed it if not because of pseudoprogression events being called progression especially in light of potential OS benefit from DCVax. Best wishes.
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