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OFP

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OFP

Re: XenaLives post# 93839

Wednesday, 03/01/2017 10:19:30 AM

Wednesday, March 01, 2017 10:19:30 AM

Post# of 460448

Your post is irrelevant as it is a collection of MMSE scores


1. AVXL chose this historical placebo group for comparison.
2. Given that they do not have a placebo arm they MUST choose a historical control group if they wish to make comparisons
3. They could have chosen matched control groups (and you can be darn sure they looked at it) but instead they chose the full group
4. This can not be irrelevant as AVXL made comparison to this group on of the highlight findings of the last data set
5. They will no doubt continue to report the full group findings and compare to this group now that they set the precedent. AVXL certainly does not find it irrelevant.
6. Examination of subgroups is always very dicey in a statistical sense and with small groups even dicier...bordering on irrelevant at best. Focus on the super responders may be of interest but it is far less relevant than the full group.
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