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Re: jq1234 post# 208101

Tuesday, 01/17/2017 10:45:29 PM

Tuesday, January 17, 2017 10:45:29 PM

Post# of 257448
In addition to likely primary analysis at 25% cutoff, trial is likely large enough for hierarchical analysis at other cutoffs.

IIRC, AZ's 25% cutoff is approx same prevalence as MRK's 50% cutoff, will be interesting to see how efficacy of CTLA4 combo compares to monotherapy in PD-L1 "strong positive"

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