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Re: kld2 post# 61231

Sunday, 05/01/2016 7:14:26 AM

Sunday, May 01, 2016 7:14:26 AM

Post# of 517493
Thanks - I also noticed these points.

Few of my additions -

1. why the media blitz from Dr mac? Typically lead PI are not so vocal - such publicity brings bias and could seen as impacting results.

2. Partnership - will be needed for P3 - it is long and expensive journey - Dr M probably does not have right resources to handle such large trial and also sustain for long time.

3. If 26 weeks results are good - hopefully we get decent BO offer from BP based on potential and as individual investors we make good money and drug goes into right hand to go toward and approval.

Here is P3 study of Biogen for their most promising ALZ drug - 1350 patients - starting in 2015 - recruitment till 2020 - results 2022
There are 2 of them

Can AVXL handle such large trials



https://clinicaltrials.gov/ct2/show/NCT02477800?term=aducanumab&rank=4
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