Amarin Corp Plc (AMRN)

[vas2]

like this part..
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Studies show that use of high-dose statin treatment
can produce an extra reduction in cardiac events,
by achievement of the maximum lowering of LDL
cholesterol.
Similar benefits could arguably be obtained
if the dose of statin was increased without the addition
of EPA; however, we noted that EPA did not affect LDL
cholesterol concentrations and that this 19% reduction
in major coronary events in the EPA group was not
related to serum LDL cholesterol. This finding suggests
that EPA exerts its effects via mechanisms that are
independent of a reduction in LDL cholesterol.
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