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Re: flipper44 post# 33669

Tuesday, 04/21/2015 8:09:34 PM

Tuesday, April 21, 2015 8:09:34 PM

Post# of 828127
Interesting ideas here Flip.

I did read your posts on Lancet - I was reading rather fast, so I'm glad to know that the technology was the older dc science, and that it still saw up to 15% ORR response.

With our more advanced technology, the more frequent and optimal dosing, I'm sure we'll see very excellent responses with Direct. We just have to be patient for the results.

Regarding DCVax-L and checkpoint inhibitors... I know I had just assumed all along they'd consider using Direct for that partnership. But your 5 reasons seem like very valid considerations.

How do you think that might work? Meaning, if the plan is to shrink the tumor, how do they make the vaccine? Do they resect a bit of it to make it? They can't make L, can they, from a blood draw?

They haven't positioned L to go after inoperable tumors, so I wonder what types of tumors they might target with a checkpoint inhibitor paired with L?

Anyhow, just a few questions based on an interesting premise.
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