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Re: thefamilyman post# 74491

Wednesday, 10/22/2014 2:03:14 PM

Wednesday, October 22, 2014 2:03:14 PM

Post# of 403025
Dose increases range from 25% to 100% and generally 25%, 33%, 50%, 66% and 75%. 75% increases are rare as are 100% occurring mostly during the early cohorts in a drug escalation.

If no AEs on cohort 9 then the next level would be 435, 460, or 525 where 525 is a 50% increase.

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