ABBV/ENTA TURQUOISE-II cirrhotic patients 12-week: Overall SVR12=92% for 3-DAA plus RBV. For trt naive, SVR12=94%; for trt experienced, SVR12=90%. http://www.nejm.org/doi/pdf/10.1056/NEJMoa1402869 [Generally speaking similar to ION-1, 2 cirrhotic patients taking consideration ION-2 included some Incivek/Victrelis treated.] SAPPHIRE-I: trt naive. http://www.nejm.org/doi/pdf/10.1056/NEJMoa1315722 SAPPHIRE-II: trt experienced. http://www.nejm.org/doi/pdf/10.1056/NEJMoa1401561