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10% off right now at Predator…
BOA charged me a $17.41 “Foreign Transaction Fee”.
I have not let the capsules dissolve under my tongue. But the way I finally got my order to go through was to type my name on the credit card form in all caps. That’s the way it’s printed on my card so…. Anyway, I tried it and it worked.
Predator finally responded to my filling out their contact form last Thursday. It did not respond to my specific issue. Instead a got a generic response. So I replied to that email as follows. “Dear Customer Service Support Team;
You did not respond to my original concern. I have now tried to place an order, for multiple bottles of Anatabloc, 7 different times using 4 different cards (3 credit cards and 1 debit card). On five of those attempts, when got my pay information entered and I clicked on the "Pay Securely" button, it just went back to order screen with no explanation or comment. On the other two times, it gave me an option to try another source of payment. I did try that but had no luck.
As I understand it, I am not the only one in the US who has had this difficulty. I have had absolutely no credit issues and all my cards are in good standing. PLEASE help me place this order! I want to once again be a customer of yours.”
I’ll keep you posted…
I have tried twice to place an order. It goes all the way thru the process and when I hit the button to submit the payment, it goes back to the order page and shows that my cart still the product in it. The first time I tried was yesterday and it never did charge my credit card. I just tried again and the same thing happened. Anybody know what’s going on? Is it because I’m in the USA?
Our previous Covid study administered Brilacidin too late in the progression of the disease. The damage caused by the virus had already been done. I’ve got to believe that if they administered an IV of Brilacidin when the patient first presented at the hospital or doctor’s office, the results would have been much more positive. And now we have evidence that it might not even matter what disease the sick person presents with. Brilacidin may well cure (or at least slow the progression or reduce the damage) of a wide variety (most?) viruses AND bacteria. It could (potentially) be the first and best line of defense if given early enough in the process.
I am still thinking that Brilacidin might work on the mild to moderate group. The two options being considered now may have the advantage of being orally administered but they have not been proven to work that great and both seem to come with major risks. I think a Brilacidin trial for those in the mild to moderate category might look something like this. The patient presents at the emergency room and a Covid infection is confirmed. A blood sample is taken to establish a baseline and the patient is then given a Brilacidin IV. Follow-up visits and/or blood samples would be utilized at appropriate intervals. Multiple doses would probably be better, but if one dose knocks the Covid back by 90%+, perhaps that is enough for the immune system to get ahead of it. It’s worth a try…
To me, the inclusion of the phrase “we wouldn’t anticipate” tells you that the statement is most certainly not “definitive”. The subjective phrase “any large effect” is another indication.
Loanranger said,
This was the statement attributed to the CEO:
"Given heparin is dosed at such low concentrations, we wouldnt anticipate any large effect of Heparin on Brilacidin's blocking property in the COVID trial." My comment ("Besides, last I heard the amount of heparin used wouldn't have had a significant effect") was consistent with that statement and I'm not sure what you mean by his statement not being definitive.
Leo’s statement was not a definitive one. It’s amazing how many times what we expect and what actually happens turn out not to be the same thing.
As to the paper, I did not see a mention of Brilacidin at that link.
It’s amazing how many times what we expect and what actually happens turn out not to be the same thing.
OldenGrumpini said,
Dr Bones contacted the IPIX CEO about the heparin effect. The response was, "Given heparin is dosed at such low concentrations, we wouldnt anticipate any large effect of Heparin on Brilacidin's blocking property in the COVID trial."
The adverse effect of Heparin was not known at the time the trial was designed. I suspect that may have had an impact as well. There are other options for a blood thinner if that adverse effect had been known at the time the trial was designed.
Petemantx said,
Dosage too low and possibly dosing not often enough the ONLY reason for the failure to reach TL objective IMO.
Apparently the adverse effects of Heparin on Brilacidin’s ability to stop the virus from entering the cell was not even suspected when the trial was designed. How badly was the trial compromised by this? It would be interesting to know how many of the patients in the Brilacidin trial were also being given Heparin.
This! These could be the same kind of small trials that resulted in the deal with AlfaSigma.
Luckytouch said,
DeGrado could give input on other indications for treatments maybe with Asthma or COPD (PDE4 and anti-inflammatory) via nebulizer. Could be done as POC P1/2 in hospital or by pulmonologist in out patient setting. Doseing determined inP1 and nebulized with an in line set with O2. That could be a low cost trial yielding lots of data and validating B via nebulizer and opening the door to Covid at early stage and competitive with the announced orals by Merk/Ridgemont and Pfizer. We can’t just roll over now. Leo is good at scrambling and surviving and this is a big challenge.
I was wondering the same thing. What were the before and after of viral load concentrations?
DrBones said,
I’m curious most about the last secondary endpoint, viral load concentrations. Did it kill the virus?
To add some more of that “perspective?.. I was afraid from the start that the patients in the “moderate to severe” category might be too far into the disease process to take optimal advantage of Brilacidin’s anti-viral capabilities. But I felt that I had to trust that all the brains involved had reason to select the moderate to severe category. Now, given the results of this trial, I am even less optimistic about those compassionate use cases. However, the mild to moderate cases should be in Brilacidin’s sweet spot. The two new drugs are both given orally (pills) but they both apparently have limited effectiveness as well as the potential for serious side effects. If Brilacidin excels in mild to moderate, it will still be the safest drug capable of making a difference for patients suffering from Covid-19 and possibly many other viruses.
Based on this and the many other irons IPIX has in the fire, I added almost 10% to my holdings today.
Irish said and I agree,
I think some perspective is required today. Brilacidin was never about Covid.
Thank you for sharing. And I sincerely hope to be found among those that you “respect and trust”.
Your involvement may not have impacted this at all. But I like the fact that you made the effort to make sure the right people had the information!
Crashco said,
In August I notified Innovation Pharmaceuticals of the publication and the findings regarding heparan. Fascinating, now, to see this follow-up(?) paper co-authored by Jun Wang, DeGrado and others.
A BP rigged their drug trial? Is anybody really surprised? Pfizer might be worried that the FDA will get very upset… but I doubt it. I’m sure that Pfizer Board Member and former head of the FDA, Dr. Scott Gottlieb, will smooth things over so there are no real consequences for the company.
TradingPro said,
Article, PFE’s drug may not be as good as they claim. Seems like they cherry picked target patients.
I recall reading about a study a few years ago where the BP used a substance in the placebo that would produce the same adverse events that they were expecting their drug to produce. That way their new drug did not look as bad because the placebo caused just as many SAEs as the drug. I do not think the FDA properly exercises oversight when it comes to BPs; so I do not trust Merck, particularly under these circumstances. The EUA will protect them from significant liability and then proving that molnupiravir caused your cancer is a very steep uphill climb anyway. It’s a perfect opportunity for an unethical company to make big money at our expense. Because of the limit on liability, the actuaries can easily predict that the costs incurred for even a significant number of deaths is worth the risk. No, I do not trust Merck.
Merck said,
…no deaths were reported in patients who received molnupiravir, as compared to 8 deaths in patients who received placebo
And we can believe what Merck says, right? Merck is, after all, selling it under an EUA so their liability is very limited. Besides that, they know that it would be hard for you to prove that their drug caused your cancer. It is a situation where it will be very easy for an unethical company to game the system at the expense of the general public.
Cabel said,
Merck has said data shows molnupiravir is not capable of inducing genetic changes in human cells…
It looks like the Pfizer drug is competition for Merck’s mutagenic drug. Both of which are for use early in the disease.
LilKahuna said,
The selling was nothing more than market reaction to the Pfizer news. The problem is, the drug is expensive. It’s fine for wealthier countries, but the rest of the world, the other 6 billion people, need a cheaper, effective treatment. Brilacidin is still in the running in dozens of markets.
Ivermectin is vindicated? Link please…
Lemoncat said,
Ivermectin is vindicated.
I suspect some of our new buyers are using Stop/Loss orders. The Market Makers (MMs) can see those orders so it is a simple matter for the MMs to manipulate the price down so they can harvest those shares.
Fanfoiz said,
MM's are playing... 0.54 to .495 in a few minutes
Amen!
Steelyeye said,
Biomanbaba is no longer on the planet, but he's no doubt smiling ... RIP
You need to add number…
9. If IPIX can get up listed by Spring, then all the Index Funds will have to initiate a position. This will bring more buying pressure (and upward momentum) to the share price.
I think that they are coming from somebody who is making a big mistake…
DrBones said,
Fills keep happening at .4396 and nothing changes, where are these endless shares coming from
Sunspotter said,
No, it doesn't. There are literally dozens of compounds that work excellently against COVID 19 in vitro, but don't work at all in vivo.
And there is remdesivir, with an SI of over 1000 (brilacidin is a mere 426) that has marginal efficacy at best.
I don’t think it’s a leak. Brilacidin worked in the lab against ABSSSI and then it worked very well in the human body against ABSSSI. It stands to reason that if it works very well in the lab against Covid, that it will also work in the human body against Covid just like it did for ABSSSI. It does the same thing to the virus that it did to the ABSSSI bacteria, so why not? That knowledge and the pending results should be enough of a word to the wise.
Shazam said,
Any chance this could be from a small, but reliable leak about TLD results? If not, that would mean a lot of new buying eyes and checkbooks on IPIX stock, which is a definite positive, but are all buying solely on the HOPE that TLD results will be good? Not sure I’m buying that theory! I think there’s a little bit of very positive confirmed info. circulating somewhere.
Is 36 cents the line in the sand this morning?
That was not my intention…
And for crying out loud, do NOT use Stop/Loss orders on any OTC stock. The market makers can see those orders and will manipulate the price down far enough to STEAL your shares. Often, you will then have to buy back in at a higher price than you were stopped out at.
I wish to read up on the liver cancer trial. Anyone know of any online info other than that provided at the link below? TIA
https://clinicaltrials.gov/ct2/show/NCT00986661?term=Provectus&draw=2&rank=10
Truth!
HereToday said,
In today’s time and with today’s current technology, there is NO JUSTIFIABLE REASON trades cannot close out same day. Either the shares are available or they are not. With the speed and way shares get traded electronically today, requiring all shares to be digitally processed and closed out each day should not be an issue at all!
The info below was news to me.
“What we found was really astonishing for us. After we inhibited the galectin1 protein, the brain tumors simply didn't grow for several months," says Arezu Jahani-Asl, an Associate Professor of Medicine at McGill University. "To improve patient response to therapy, we must exploit these newly identified vulnerabilities in cancer stem cells."
Fighting brain cancer at its root
https://medicalxpress.com/news/2021-08-brain-cancer-root.amp
It’s called painting the tape…
Williamssc said,
Looks like someone desired for it to close red.
Technically, the PR could be posted at 11:59PM next Sunday night and still be within the previously posted timeframe. That could certainly make for an interesting Monday morning on November the 1st!
My condolences to you and his family. Every time I hear a story such as this I find myself wondering if Brilacidin could have helped…
Here’s a bacterial infection that we may find is cured by Brilacidin’s delayed release pills for Crohn’s and IBD.
Linda Ann Sasser has had ulcerative colitis since she was 20, but it wasn’t until May 2019, about 30 years later, that her condition hit a low point: not only did she have a major flare-up of chronic inflammatory bowel disease (IBD), but on top of it, she had Clostridioides difficile (or C. diff), a highly contagious bacterial infection that causes severe diarrhea and inflammation of the colon. “I became really, really sick with bloody diarrhea 30 times a day and chronic stomach pain,” Sasser says. While hospitalized for 12 days, she was given oral steroid medications, which didn’t help, then IV steroid medications, which gradually improved her ulcerative colitis flare-up. The next challenge was to treat the C. diff infection. The doctors tried antibiotics, which didn’t get the job done; Sasser’s abdominal pain was incessant, and the diarrhea would come on so suddenly that she often couldn’t get to the bathroom in time. “I was at the point where I said, ‘Just take out my colon,’” she recalls. Her doctor told her about another treatment that might help: fecal microbiota transplantation (FMT), which is exactly what it sounds like: fecal matter (as in: stool) from a healthy donor is transplanted into the body of someone like Sasser in the hope that it will improve her health… …Right now, FMT is considered an experimental therapy—that is, it has not been approved by the Food and Drug Administration (FDA) for any uses; however, the FDA exercises “enforcement discretion” regarding the use of FMT to treat C. difficile infections that haven’t responded to standard treatments (such as use of the antibiotics fidaxomicin or vancomycin), provided that donors are thoroughly screened and patients are thoroughly informed about the potential benefits and risks of FMT. Meanwhile, it has become a hot area for research for IBD, obesity, cardiovascular disease, auto-immune disorders, diabetes, metabolic syndrome and other medical conditions.
https://time.com/6096395/fecal-transplants/
I think you mean “disingenuous”.
Billy10us said in response to Mxamdud,
Your advice is dangerous and so ingenuous.
Rdunn said,
You honestly believe there's life after 18 months of non-stop hype?
The PPS couldn't recover with B for C?
How would anyone expect IPIX to survive a COVID fallout?
Leo would have to remove all B for C website info like Pruriol....
The RBL experiments would be dropped.
Leo would crawl back to Locust Walk?
They're toast without good data...