Innovation Pharmaceuticals Inc (IPIX)

[thefamilyman]

Here’s a bacterial infection that we may find is cured by Brilacidin’s delayed release pills for Crohn’s and IBD.

Linda Ann Sasser has had ulcerative colitis since she was 20, but it wasn’t until May 2019, about 30 years later, that her condition hit a low point: not only did she have a major flare-up of chronic inflammatory bowel disease (IBD), but on top of it, she had Clostridioides difficile (or C. diff), a highly contagious bacterial infection that causes severe diarrhea and inflammation of the colon. “I became really, really sick with bloody diarrhea 30 times a day and chronic stomach pain,” Sasser says. While hospitalized for 12 days, she was given oral steroid medications, which didn’t help, then IV steroid medications, which gradually improved her ulcerative colitis flare-up. The next challenge was to treat the C. diff infection. The doctors tried antibiotics, which didn’t get the job done; Sasser’s abdominal pain was incessant, and the diarrhea would come on so suddenly that she often couldn’t get to the bathroom in time. “I was at the point where I said, ‘Just take out my colon,’” she recalls. Her doctor told her about another treatment that might help: fecal microbiota transplantation (FMT), which is exactly what it sounds like: fecal matter (as in: stool) from a healthy donor is transplanted into the body of someone like Sasser in the hope that it will improve her health… …Right now, FMT is considered an experimental therapy—that is, it has not been approved by the Food and Drug Administration (FDA) for any uses; however, the FDA exercises “enforcement discretion” regarding the use of FMT to treat C. difficile infections that haven’t responded to standard treatments (such as use of the antibiotics fidaxomicin or vancomycin), provided that donors are thoroughly screened and patients are thoroughly informed about the potential benefits and risks of FMT. Meanwhile, it has become a hot area for research for IBD, obesity, cardiovascular disease, auto-immune disorders, diabetes, metabolic syndrome and other medical conditions.

https://time.com/6096395/fecal-transplants/