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Did I miss the $20 opening price today?
SO I am a little confused. Why would AVXL send out an update indicating a release of quarterly earnings after the close on the day before Thanksgiving? Obviously they would know the mentality of the investment community would anticipate the impending results or updates would not be the greatest.
1) If the update would be negative, wouldn't it have been better to release the results not on that particular day, and if there is a decline or disappointment than so be it. Can't be any worse than it is now as this would be a decline prior to results and even worse if results are less than favorable.
2) If the result would be positive, trying to burn some shorts ( which you would have burned at a higher price anyways, or could this be a favor for someone to get in at lower prices.
Either way doesn't make any sense to announce an earnings release on the day before Thanksgiving and markets closed.
Anyone else
same , before she was even on second semtence
Question is where is the boom ? Premarket only 1472 in volume. Surprising for sure.
Not sure if this has been posted:
Promising’ Alzheimer’s pill could stop disease in its tracks, human trials to start soon
by Study Finds
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BOSTON — Although there’s no cure for Alzheimer’s disease yet, a new drug that could come in pill form is giving hope to millions of dementia patients around the world. Researchers say the potential Alzheimer’s drug prevents the disease in mice, rats, and monkeys during lab experiments.
The results are so “promising,” researchers expect clinical trials to begin in the next few months. Such a drug may also ward off the cognitive breakdown in genetically prone people who don’t have the condition yet. Study authors say vulnerable individuals would be able to get the medication after a simple blood test.
Targeting plaque buildups in the brain
A team from the University of California San Diego School of Medicine and Massachusetts General Hospital say the treatment belongs to a family of drugs called GSMs (gamma-secretase modulators). It works by destroying rogue proteins, beta-amyloid (Aß), that form sticky clumps in the brain and destroy neurons.
Amyloid plaques
Compared with a control (left), treatment with the novel GSM (right) reduces the number of amyloid plaques (green) and proinflammatory cells called microglia (magenta) in the brains of mice carrying mutations linked to early-onset Alzheimer’s disease.
“In this study, we have pharmacologically characterized a potent GSM that, based on its preclinical attributes, appears to equal or exceed the potency of any previously tested GSMs,” says lead co-author Dr. Rudolph Tanzi in a media release. “Future clinical trials will determine whether this promising GSM is safe in humans and could be used to effectively treat or prevent Alzheimer’s disease.”
The researchers are awaiting approval from the U.S. Food and Drug Administration for phase 1 studies to begin.
“We hope to get started this year. It would be a typical single and multiple ascending dose in healthy individuals. If we are get through phase 1, phase 2A would be in Alzheimer’s patients and include looking at biomarkers for reducing beta-amyloid in the brain,” Dr. Tanzi adds in a statement to SWNS.
“Ultimately, we hope our gamma secretase modulators will be sufficiently safe and effective for use in preventing Alzheimer’s – similar to how we use statins to prevent heart disease,” the Massachusetts General Hospital researcher and Professor of Neurology at Harvard continues. “Just like we have to lower cholesterol levels early in life, for decades, to avoid heart disease later in life, we will need to lower brain beta-amyloid levels early in life, for decades to reduce risk for Alzheimer’s. This means the drug we use to do that must be safe, inexpensive and easy to administer – for example, a small molecule pill.”
What makes normal proteins trigger Alzheimer’s?
Beta-amyloid is a normal protein. Everyone has it. In Alzheimer’s patients however, the process for flushing these proteins out goes awry. Other enzymes, including gamma-secretase, fuel small fragments, or Aß peptides. The body can’t recognize these so it’s unable to get rid of them.
Hmmm,
Lucy trying to pull the ball again.
Agreed completely, was just thinking the same thing. This is nothing but an attempt to rid the last band of shareholders. How the past few years(decades) of the stuff that has gone here is not a blatant criminal thievery is beyond me.
8 million for 245 million invested in IP, and then selling shares at 30% discount is a joke and it’s still kick the can down the road.
I hate to say it, my wife was right years ago when she told me this was a pipe dream
CP
"Do we want that party in control of PPHM through 3 BoD members, the Broker Non-Vote control and an about 9% position?"
If you are asking my opinion, than hands down, I would take this party over the current 3 BOD members who have no skin in the game. I will let a 9-10% owner run the company since they would have an incentive to make us and them as much money as possible. I don't think I need to go in to the failures/mishaps and mistakes this current BOD have been involved with, on top of the two reverse splits and their excessive compensation.
I understand your concerns with replacement of current BOD, but if there is a choice I would take the Ronin group. After 15 years of failure, you don't get a free pass anymore. It's almost comical/ criminal these guys are still there. Can you imagine this BOD at any other legit company, do you honestly believe they would still be there.
In addition what does it say about our current BOD that if Ronin didn't buy over the last few months we would be pre split .30.
Any support for current BOD in my opinion is the same status quo. If these guys were truly legit, they would have cut their compensation years ago.
We will have to see if Ronin has the two guns to shoot the current board and win, I believe he may, but know there are a bunch of retail as well, who may have some small shooters to join him. It's a chess game at this time and I don't put to much confidence in this board's ability to think ahead so many moves.
Don't see any incentive for Ronin to keep buying at the moment. He may let the price languish, so we are even more pissed off with this current BOD. And of course the current board will only oblige buy selling shares ATM.
Sounds like this deal may have already been made behind back doors. We all better pay careful attention here, this is going to be very interesting indeed!!
What a surprise, Lucy pulled the ball!!
Like I said, something smells fishy, this is no doubt a deliberate attempt to sabotage this company.
That's nice to know, ty
Definitely would be interested in Dart's take here, and how much influence he has as well. Does anyone recall what price he is in at?
Anyone else think we blow through HOD before end of day?
Funday Friday tomorrow!!
And it should be concerning to you, however not a surprise, there have been people here that have continued to support this management team for years, despite their failures. Makes you really wonder.
When has there ever been good news on a Friday afternoon conference call. Don't hold your breath. Another middle finger on a Friday.
"Lots of ways to manipulate the pps and manipulate Peregrine into a RS which hurts current shareholders and would help a future partner "
No manipulation here, clear as day, they chose to sell ATM. With all the buying Ronin had been doing , this would have easily eclipsed a buck. If there is any shenanigans going on or any complaints to the SEC, it would be clear to pinpoint .
WHY WERE THERE SO MANY SHARES SOLD ATM AT A TIME WHERE MANAGEMENT HAD A FIDUCIARY RESPONSIBILITY TO KEEP THIS OVER A DOLLAR .
Hello folks not rocket science here. Of course if this RS does not reduce shareholder value, than maybe there is no issue, but does someone in the know benefit because of the RS and the holdback of share price appreciation.
I think either way this management team is screwed, or BOD. Interesting times indeed
Should be doubled up at least today. As our friend Couch has said a million times " everything and anything under ..." fill in the blank. It's almost comical to see most of us longs still hanging on here, PPHM the stock should be approved for a drug!!
Good luck longs, let's hope for something soon ( not PPHM soon).
These clowns/criminals really need to go, we have been saying it for years.
Without question, this has been nothing but an orchestrated attempt. This BOD has been keeping the lid on the share price for reasons we are not aware ( greed, control, or other reasons). You do not sell millions of shares for .60 or less ( wouldn't be surprised if they are selling today) knowing your share price will be over $4 unless you have intentionally thought out a strategy in your own mind. We better hope that Ronin is involved somehow, as I can't imagine he would buy all those shares in order to take a 20% hit.
Either way there is no doubt in my mind their is collusion and some fiduciary breach of duty or criminal activity. With that said, I picked up another 14,000 shares at .51, lol, gotta have balls here I think.
Ronin is the key in my opinion, hoping for something big, but he has got to be a lot smarter than me, so follow the money!!!
Doesn't take much to put the puzzle pieces together. If you are trying to avoid a reverse split and the price is being run up on a major purchase, and you have a chance to get over a dollar, you don't sell into the ATM.
This BOD has no concern for shareholder value, and hence this is why people talk about lawsuits. A complete breach of not only fiduciary responsibility, but also a lack of any business prudence.
Very easy to sell at the ATM after the reverse split is avoided. For anyone to stick up for this board only makes you wonder who and why are aligned with this board, its amazing to me the number of posts that are made on a positive basis at the edge of the bleakest of times. Who knows a pump and then a short.
Let's get the reverse split over with.
Saw that on tv as well. A 39% complete remission in patients, Immunotherapy was plastered all over the screen, saw MD Anderson and ( I forget the other they mentioned) and thought here we go, only to hear CAR-T.
Hopefully some day.
Just out of curiousity does anyone know the date the appeal of the reverse split has to be filed by, and is that a necessary PR. If I am not mistaken isn't March 24 a specific deadline?
Anyone find it interesting we've seen no comments from AF for Dew diligence, May be a little hit piece tomorrow so Ronin can grab some more shares.
Interesting indeed
If the powers be want to grab some shares from retail, they will have to move this up past the .72 mark to free some up, looks like everyone staying pat.
We may see some great volume today, even though a Friday. Over 10 million would be nice. Let's go with 4 million in the first hour. This ship is about to sail.
Doubt it, but Ronin and Dart together would have a nice chunk and may work together.
I guess we know now where the volume started from. Very interesting and confident move indeed.
Stransberry report mentioned the same thing about biogen, and again nothing about Anavex.
Do not feed the trolls, lol
We will chip away at this block of 5.84, and off running again.
link for webcast
Golden crosses are nice!!
Do we have something today, don't see anything on the anavex website( earnings/presentation?)
Lets break that wall at 4.67, and off we go
Estimated .03 loss per share on revenue of ~18 million, how much revenue will we need to break even. I am thinking 32 million with a 40% profit margin on revenue
Any predictions for the last hour here, blasting past 5, or retracing back a bit to lock in profits. Are the tea leaves telling us anything? Should be an interesting call!!
I got sucked in for the same, although I grabbed mine at .375. When will we ever learn, lol, but 9.0 million shares, hmmm, something may be up?
300K block, someone looking to get out or trying to keep us down
Love that green candle at end of day and HOD, tomorrow should be fun