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ciotera

04/03/14 1:29 PM

#176330 RE: caravon #176328

GILD Cirrhosis



Over 200 patients across ION 1&2 were cirrhotics. With ~98% overall SVRs, under the most conservative assumption (100% SVR in non-cirrhotics), SVR in cirrhotics is still 90%. Which is good enough, but it's likely higher. ABBV can message their Turquoise data specifically generated for this population and this may confer a marketing advantage, but I doubt there is a real clinical advantage here.
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caravon

04/03/14 2:39 PM

#176333 RE: caravon #176328

Is there some statistics for HCV without cirrhosis vs. with cirrhosis pts population?

Tia
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DewDiligence

04/03/14 3:19 PM

#176341 RE: caravon #176328

GILD will presumably disclose the cirrhotic subset data from ION-1 and ION-2 at EASL; let’s defer this discussion until then.