Its exactly what is going on and makes things more critical in getting a big partner on board. The Calico angle would be big as well because you need a partner with DEEP DEEP pockets, if you want to fight the establishment.
I stated before that I've seen many of companies with the best technology get squashed by the big players in that field. Having the best mouse trap means squat, if you can't get through all the regulatory hurdles, competitive battles, political nuances and Wall Street corruption. Bavi may be the Holy Grail for many diseases, but it really is worth shit without the ability to bring this platform to market.