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Protector

01/28/14 8:51 AM

#158295 RE: sulaco #158258

sulaco, good reasoning. I will not gamble and follow your "Merck is the partner" although it could be, I just don't know.

I would however like to add one little detail. When they wrote that Merck's anti-PD1 drug is worth 6 Billion $, they mean 6 Billion Dollar A YEAR! <<<IMO :)

So the question is, will their be ONE and ONLY ONE anti-XYZ in the final play (at least per condition) or will CTLA-4, PD-1 and others compete?

->If the answer would be NO:
Then being the winner is of MAJOR importance and Merck, Roche/Genetech, BMY etc will fight amongst them and to win (no matter how good they are on their own) the NEED BAVI! In all other cases they can berry their research and take their losses and very probably leave the related oncology markets (as I wrote before EXISTENTIAL for at least the Oncology departments).

->If the answer would be YES:
Then the patients will want the best and for the involved BP's to at least compete at a profitable level (get a reasonable market share) they need to massage THEIR companies FRIENDLY Doctors to drive the patient to their product. It is know Doctors do that BUT not if the gap is to big with competing products. So they ALL need Bavi to keep their results as close as possible to the better product.

Bottom line: PPHM with Bavituximab ALWAYS wins.

I would therefore say (depending on price setting of course) that it may well be that Bavituximab is the only one in the game that may be worth the said 6 Bilj$ because in the worst case scenario the BP's may have to share their part of the anti-XYZ's pie between them.
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biopharm

06/23/16 8:00 PM

#267271 RE: sulaco #158258

Merck's $6 Billion drug would make Bavi/PPHM $35/share


If Merck's anti-PD1 drug beats BMS Yervoy (and it looks like it already has), and is worth $6 Billion, then what's Bavi worth?

Well, if Bavi is worth $6 Billion,, that puts PPHM at $35 bucks a share, + Avid, + Betabodies, + imaging, + Cotara. Add your typical multipliers and forward earnings in , and you'll see why folks can get a little animated around here.

When analysts say a Merck immunotherapy drug looks like a $6 Billion dollar drug, that should catch EVERYONE'S attention.

Bavi turns on the upstream lights for the downstream "anti-XYZ'ers" (as CP calls them). Merck will need Bavi and the anti-PS platform.

Their diabetes and cholesterol drug proftis are tanking and they're missing profit forecasts.

Mercks Big Earnings Miss

Their shareholders are best described as an unruly drunken mob.


Merck is an incredibly proud company with a very long history. But they've been slipping. They're like the Yankees. When they don't make the playoffs, (earnings) they then go out and pursue every talent out there to make sure it doesn't happen again.

I'll go so far as to predict that MERCK will be the partner for Bavi.

Why? Because they're winning the downstream anti-XYZ war. But they need the one upstream player out there: Bavi.

That's my call: MERCK


Best,

Joe



Joe, what do you think of Merck and playing with Bavituximab now?