Enta-Dew, i refer to the ribavirin arms. I know, sapphire was not rib-free. My argument is: When i take 450+267 (pearl 1) then i get 95% (naive) 90% (treated). When i take 450+267+333 the SVR12 minimum must be the svr12 that we seen in pearl 1. The maximum in the 450+267+333 regime without rib would be the svr12 that we seen in the regime with rib (sapphire 1/2).