Replies to post #22670 on Biotech Values

[St_armands_man]

ENMD/MKC-1 cellular target?

I don't recall it being discussed anywhere. Probably lost in all of the changing of hands. I'm at work right now (my real job) but I'll take a look later and see if I can find anything.

MKC-1 is an orally-active, novel, small molecule, cell cycle inhibitor with a unique mechanism of action. Specifically, MKC-1 arrests cellular mitosis by inhibiting a novel intracellular target important in cellular trafficking that has been shown to be involved in cell division. In preclinical studies, MKC-1 demonstrated impressive activity in a broad range of tumour models.