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Give to Mayo Clinic You are an essential partner in our work to find answers for our patients. Donate now. CLINICAL TRIALS Clinical TrialsAbout Clinical StudiesDeciding to VolunteerContact Advanced search Scrambler Therapy for the Treatment of Chemotherapy Induced Peripheral Neuropathy: An Open Access Trial
LOCATION: Rochester, Minn.
TRIAL STATUS: Open for Enrollment WHY IS THIS STUDY BEING DONE? OBJECTIVES: I. To record the types of patients that we treat, along with the reported efficacy and potential toxicity associated with scrambler therapy. II. To get experience with patient reported outcome measurement tools that we use in this trial, including a report of analgesic use. OUTLINE: Patients undergo scrambler therapy for 30 minutes daily for up to 10 consecutive days. Treatment continues in the absence of unacceptable toxicity. After completion of study treatment, patients are followed up for 10 weeks. III. To explore neurologic testing changes in patients receiving scrambler therapy.
WHO IS ELIGIBLE TO PARTICIPATE? Inclusion Criteria: - Pain or symptoms of neuropathy or pain of >= 1 month (30 days) duration for which the patient wants intervention - Participants have to relate that tingling or pain was at least a four out of ten problem during the prior week, on a 0-10 scale where zero was no problem and ten was the worst possible problem and expected to have tingling or pain of at least 4/10 at the time of the first treatment - Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) = 0, 1, or 2 - Life expectancy >= 3 months (90 days) - Case review by the study chair, or designate, as a case where treatment should be tried. - Ability to complete questionnaire(s) by themselves or with assistance - Ability to provide informed written consent Exclusion Criteria: - Pregnant women - Patients with implantable drug delivery systems, e.g. Medtronic Synchromed - Patients with heart stents or metal implants such as pacemakers, automatic defibrillators, aneurysm clips, vena cava clips and skull plates; (metal implants for orthopedic repair, e.g. pins, clips, plates, cages, joint replacements are allowed as are central venous access devices) - Patients with a history of myocardial infarction or ischemic heart disease within the past six months - Patients with history of epilepsy, brain damage, use of anti-convulsants for seizure prevention, concurrently using ketamine, symptomatic brain metastases; Note: anti-convulsant use is allowed for neuropathy and heart failure (HF) if on a stable dose - Skin conditions such as open sores that would prevent proper application of the electrodes - Other medical or other condition(s) that in the opinion of the investigators might compromise the objectives of the study - Currently on gabapentin or pregabalin Note: (because of data that support that patients don't do as well when on gabapentin or pregabalin, all patients on these medications will be weaned off of them prior to study initiation. The study team will provide instructions on how to do this).
LAST UPDATED: 9/5/2013 NCT ID: NCT01347723 IRB NUMBER: 11-000675
Wow, it's pretty sad when someone tries to deny a new 52 week low at 12 CENTS a share by saying that actually "the bid was .13 for 10,000 shares at the time and we traded only 1700 shares in the 12's..."
Somehow that doesn't seem to mitigate the FACT that 1700 shares were sold at a new 52 week low of TWELVE cents a share.
Come to think of it, that was actually an ALL-TIME LOW of 12 CENTS a share, wasn't it?
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