By definition, RVR refers to the response at 4 weeks.
Fair enough, but 100% of VX-135 patients had undetectable levels at week 12 so it still seems to get the job done and, again, may end up being used as one piece of an HCV DAA combo (preferably in combo with simeprevir -g-). Obviously, there is still plenty of work to be done to prove the drug is safe and get it off the hold of the 200mg dose.
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