Replies to post #164021 on Biotech Values

[hirogen]

XOMA-

From the abstract you posted:

Quote: Variance component analysis determined that 87.7% of the variance in grades was attributable to the test item rather than to grader or session.

That’s an impressive degree of objectivity that almost certainly surpasses the level achievable with BCVA (where even a slight forward movement of the body or head can materially affect the measurement by shortening the distance between the eye and the reading chart).

Yes, but the 87.7% came from the more tightly controlled computer based grading method using the proposed 9 point VH scale. I don't know how the proposed scale would map to the SUN/NEI system. Also linked in the paper was an abstract to a study done on the SUN VH scale. Intragrade concordance was middling at .53. Concordance within 1 grade improved to .75, but that represents half the scale range.

http://www.ncbi.nlm.nih.gov/pubmed/18687418