The inclusion of GT1 patients in this Sofo/Riba study is nothing more than an shallow attempt to suggest longer durations have wider merit. Since GS-5885 is a safe and tolerable drug which allows for 12-week dosing (or less) in GT1 why would GILD push out studies to 16 and 24-weeks? I think GILD should make sure their combo works sufficiently well in the absence of ribavirin before they consider dropping the NS5A.
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